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One Health Publications
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Found 1623 Matching Results. View archived Publications Here. |
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Renin-Angiotensin System Blockers and the COVID-19 Pandemic At Present There Is No Evidence to Abandon Renin-Angiotensin System Blockers March 25, 2020 : |
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Saturday, March 28, 2020. |
Renin-Angiotensin System Blockers and the COVID-19 Pandemic
At Present There Is No Evidence to Abandon Renin-Angiotensin System Blockers
March 25, 2020
https://www.ahajournals.org/doi/abs/10.1161/HYPERTENSIONAHA.120.15082
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Q&A: Laura Kahn *02 on COVID’s Spread and How We Defeat It |
Princeton Alumni Weekly (USA) |
Thursday, March 26, 2020. |
Life of the Mind
Published online March 25, 2020
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World Health Organization (WHO) to fund Antimicrobial Resistance (AMR) research projects in 7 countries |
Centers for Infectious Disease Research and Policy (University of Minnesota) March 24, 2020 |
Wednesday, March 25, 2020. |
University of Minnesota
WHO to fund AMR research projects in 7 countries
“The World Health Organization's (WHO's) Special Programme for Research and Training in Tropical Diseases (TDR) announced late last week that 13 projects from 7 countries have been awarded funding for research on antimicrobial resistance (AMR). ...”
“... The projects emphasize a One Health approach to AMR, looking at the human, animal, and environmental drivers of drug-resistant infections. ...”
http://www.cidrap.umn.edu/news-perspective/2020/03/news-scan-mar-24-2020 |
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New study explores the benefits of a One Health approach to investigating antimicrobial resistance in Vietnam |
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Tuesday, March 24, 2020. |
Wednesday 11 March 2020
New study explores the benefits of a One Health approach to investigating antimicrobial resistance in Vietnam
"The One Health concept promotes the enhancement of human, animal and ecosystem health through multi-sectoral governance support and policies to combat health security threats.
In Vietnam, antimicrobial resistance in animal and human health settings poses a significant threat, but one that could be minimised by adopting a One Health approach to antimicrobial resistance surveillance. ..."
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Pertinent to current Pandemic COVID-19 containment reasoning |
Community Mitigation Guidelines to Prevent Pandemic Influenza — United States, 2017 |
Wednesday, March 18, 2020. |
Pertinent to current Pandemic COVID-19 containment reasoning: Community Mitigation Guidelines to Prevent Pandemic Influenza — United States, 2017 https://www.cdc.gov/mmwr/volumes/66/rr/rr6601a1.htm#_blank
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Impact of non-pharmaceutical interventions (NPIs) to reduce COVID-19 mortality and healthcare demand |
16 March 2020 Imperial College COVID-19 Response Team DOI: https://doi.org/10.25561/77482 |
Wednesday, March 18, 2020. |
16 March 2020 Imperial College COVID-19 Response Team DOI: https://doi.org/10.25561/77482 Page 1 of 20
Impact of non-pharmaceutical interventions (NPIs) to reduce COVID-19 mortality and healthcare demand
https://www.imperial.ac.uk/media/imperial-college/medicine/sph/ide/gida-fellowships/Imperial-College-COVID19-NPI-modelling-16-03-2020.pdf
Summary
The global impact of COVID-19 has been profound, and the public health threat it represents is the most serious seen in a respiratory virus since the 1918 H1N1 influenza pandemic. Here we present the results of epidemiological modelling which has informed policymaking in the UK and other countries in recent weeks. In the absence of a COVID-19 vaccine, we assess the potential role of a number of public health measures – so-called non-pharmaceutical interventions (NPIs) – aimed at reducing contact rates in the population and thereby reducing transmission of the virus. In the results presented here, we apply a previously published microsimulation model to two countries: the UK (Great Britain specifically) and the US. We conclude that the effectiveness of any one intervention in isolation is likely to be limited, requiring multiple interventions to be combined to have a substantial impact on transmission.
Two fundamental strategies are possible: (a) mitigation, which focuses on slowing but not necessarily stopping epidemic spread – reducing peak healthcare demand while protecting those most at risk of severe disease from infection, and (b) suppression, which aims to reverse epidemic growth, reducing case numbers to low levels and maintaining that situation indefinitely. Each policy has major challenges. We find that that optimal mitigation policies (combining home isolation of suspect cases, home quarantine of those living in the same household as suspect cases, and social distancing of the elderly and others at most risk of severe disease) might reduce peak healthcare demand by 2/3 and deaths by half. However, the resulting mitigated epidemic would still likely result in hundreds of thousands of deaths and health systems (most notably intensive care units) being overwhelmed many times over. For countries able to achieve it, this leaves suppression as the preferred policy option.
We show that in the UK and US context, suppression will minimally require a combination of social distancing of the entire population, home isolation of cases and household quarantine of their family members. This may need to be supplemented by school and university closures, though it should be recognised that such closures may have negative impacts on health systems due to increased absenteeism. The major challenge of suppression is that this type of intensive intervention package – or something equivalently effective at reducing transmission – will need to be maintained until a vaccine becomes available (potentially 18 months or more) – given that we predict that transmission will quickly rebound if interventions are relaxed. We show that intermittent social distancing – triggered by trends in disease surveillance – may allow interventions to be relaxed temporarily in relative short time windows, but measures will need to be reintroduced if or when case numbers rebound. Last, while experience in China and now South Korea show that suppression is possible in the short term, it remains to be seen whether it is possible long-term, and whether the social and economic costs of the interventions adopted thus far can be reduced.
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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study |
The Lancet - March 9 2020 |
Friday, March 13, 2020. |
Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
Published Online, The Lancet March 9, 2020 https://doi.org/10.1016/ S0140-6736(20)30566-3
Summary
Background Since December, 2019, Wuhan, China, has experienced an outbreak of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Epidemiological and clinical characteristics of patients with COVID-19 have been reported but risk factors for mortality and a detailed clinical course of illness, including viral shedding, have not been well described.
See: https://www.thelancet.com/pb-assets/Lancet/pdfs/S014067362305663.pdf
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The effort to fight emerging infectious diseases must be holistic |
The Hill |
Tuesday, March 10, 2020. |
The effort to fight emerging infectious diseases must be holistic
Many scientists, scholars and practitioners working in the field of One Health, which promotes a holistic approach to environmental, animal, food and ...
“... Fortunately we can draw upon insights from recent interdisciplinary initiatives. Many scientists, scholars and practitioners working in the field of One Health, which promotes a holistic approach to environmental, animal, food and human health, have advocated for a variety of policy and governance interventions. These strategies address trade and illegal harvest of wildlife, land use changes that promote the emergence of EIDs and the need for targeted global surveillance to identify novel pathogens. The Planetary Health Alliance is a consortium of universities, NGOs, research institutes and government entities around the world focused on understanding and addressing the health impacts of global environmental change. These and other groups have found strong evidence that disease regulation is an important ecosystem service that remains under appreciated by the public and decision-makers. This issue is likely to be a discussion point at upcoming international congresses like the Convention on Biological Diversity and the IUCN World Conservation Congress. ...”
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